Mitochondrial Localization of SARM1 in Acrylamide Intoxication Induces Mitophagy and Limits Neuropathy

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

Life Sciences, Genetics, Neuroscience +17

Analysis of Acrylamide, a Carcinogen Formed in Heated Foodstuffs

Eden Tareke, Per Rydberg, Patrik Karlsson et al. · Journal of Agricultural and Food Chemistry · 2002 · 2.2K citations

Agriculture, Food Science, Toxicology +17

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice

Fiona Pickford, Eliezer Masliah, Markus Britschgi et al. · Journal of Clinical Investigation · 2008 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +17

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration

Kow Essuman, Daniel W. Summers, Yo Sasaki et al. · Neuron · 2017 · 638 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +12

Marked Protection by Moderate Hypothermia after Experimental Traumatic Brain Injury

Guy L. Clifton, Ji Y. Jiang, Bruce G. Lyeth et al. · Journal of Cerebral Blood Flow & Metabolism · 1991 · 530 citations · Full text

Medicine, Neurobiology, Neuroscience +15