TBK1-medicated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

Life Sciences, Biochemistry, Molecular Biology +6

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +17

Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

J. Thomas Cribbs, Stefan Strack · EMBO Reports · 2007 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints

Daniel Prieto‐Alhambra, Andrew Judge, M K Javaid et al. · Annals of the Rheumatic Diseases · 2013 · 932 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16