Cell Metabolism · 2022 · 341 citations · 21 references
MedicineImmunologyOncologyCancer ImmunologyTumor ImmunologyTumor MicroenvironmentAntitumor T Cell ResponsesCancer ImmunotherapyCytotoxic T Lymphocyte ResponsesMetabolic ReprogrammingT Cell Responses To TumorsTumor-infiltrating LymphocytesAntitumor Immune ActivationCd8 Positive T Cell ResponsesCd8 Positive T CellsCd8 T Cell ActivationCd8+ Tumor-infiltrating LymphocytesPyruvate MetabolismPyruvate OxidationSuccinate Metabolism
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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.2K citations · Full text
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
Se Jin Im, Masao Hashimoto, Michael Y. Gerner et al. · Nature · 2016 · 2.1K citations · Full text
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
Almut Brand, Katrin Singer, Gudrun E. Koehl et al. · Cell Metabolism · 2016 · 1.9K citations · Full text
Life Sciences, Immunology, Oncology +12
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Ping‐Chih Ho, Jessica Bihuniak, Andrew N. Macintyre et al. · Cell · 2015 · 1.4K citations · Full text
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
Alison E. Ringel, Jefte M. Drijvers, Gregory J. Baker et al. · Cell · 2020 · 768 citations · Full text
Medicine, Cancer Biology, Oncology +16