Concepedia

Broadening prime editing toolkits using RNA-Pol-II-driven engineered pegRNA

Shisheng Huang, Zhenwu Zhang, Wanyu Tao, Yao Liu, Xiangyang Li, Xiaolong Wang, Javad Harati, Peng‐Yuan Wang, Xingxu Huang, Chao‐Po Lin

Molecular Therapy · 2022 · 30 citations · 30 references

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30

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis et al. · Nature · 2019 · 4.7K citations · Full text

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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Sangsu Bae, Jeongbin Park, Jin‐Soo Kim · Bioinformatics · 2014 · 2.4K citations · Full text

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A more efficient method to generate integration-free human iPS cells

Keisuke Okita, Yasuko Matsumura, Yoshiko Sato et al. · Nature Methods · 2011 · 2.1K citations · Full text

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CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

Emma Haapaniemi, Sandeep K. Botla, Jenna Persson et al. · Nature Medicine · 2018 · 1.3K citations · Full text

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p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

Robert J. Ihry, Kathleen A. Worringer, Max R. Salick et al. · Nature Medicine · 2018 · 1K citations

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