Concepedia

Point Mutations

Point Mutations is a type of genetic mutation characterized by the substitution, insertion, or deletion of a single nucleotide base in the DNA sequence, thereby altering the genetic code at a specific locus.

9.4K

Publications

691.1K

Citations

50.2K

Authors

6.3K

Institutions

Publications per year

2017–2026

1.3K

Variants

Point Mutation

Parents

Publications

9.4K

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

, , +17

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

, , +14

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth, Michael D. McLellan, Fabio Vandin et al. · Nature · 2013 · 4.5K citations · Full text

, , +17

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Siân Jones, D. Williams Parsons, Jimmy Lin et al. · Science · 2008 · 4K citations · Full text

, , +12

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

, , +16

1–5 of 9.4K

Authors

50.2K

  1. WG
    William G. Thilly

    Massachusetts Institute of Technology, United States

    20 publications · 1.4K citations

    17

    h-index

  2. AB
    Alexis Brice

    Inserm, France

    15 publications · 4.8K citations

    14

    h-index

  3. DS
    Demetrios�� Spandidos

    University of Crete, Greece

    14 publications · 392 citations

    13

    h-index

  4. XL
    Xili Liu

    China Agricultural University, China

    15 publications · 541 citations

    12

    h-index

  5. FB
    Francis Barany

    Cornell University, United States

    12 publications · 1.2K citations

    12

    h-index

1–5 of 50.2K

Institutions

6.3K

  1. Harvard University

    Cambridge, United States

    88 h-index

    717 publications

    130.7K citations

  2. Inserm

    Paris, France

    83 h-index

    1.2K publications

    125.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    76 h-index

    408 publications

    84.9K citations

  4. National Institutes of Health

    Bethesda, United States

    72 h-index

    597 publications

    106.7K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    70 h-index

    880 publications

    73.2K citations

  6. National Cancer Institute

    Bethesda, United States

    63 h-index

    424 publications

    73.2K citations

  7. University of Washington

    Seattle, United States

    57 h-index

    420 publications

    51.2K citations

  8. Johns Hopkins University

    Baltimore, United States

    56 h-index

    408 publications

    222.4K citations

1–8 of 6.3K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 384 publications · 60.3K citations

    138

    h-index

  2. Journal of Biological Chemistry

    JBC · 376 publications · 29.5K citations

    93

    h-index

  3. Journal of Virology

    JVI · 280 publications · 23.5K citations

    88

    h-index

  4. PubMed

    Repository · 438 publications · 33.4K citations

    88

    h-index

  5. Nucleic Acids Research

    286 publications · 34.2K citations

    80

    h-index

1–5