On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

Medicine, Neuroscience, Surgery +17

Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products

Robert A. Floyd, Julia Watson, Peter K. H. Wong · Journal of Biochemical and Biophysical Methods · 1984 · 394 citations

Natural Sciences, Biochemistry, Chemistry +17

Aromatic hydroxylation as a potential measure of hydroxyl-radical formation <i>in vivo</i>. Identification of hydroxylated derivatives of salicylate in human body fluids

Martin Grootveld, Barry Halliwell · Biochemical Journal · 1986 · 375 citations · Full text

Life Sciences, Biochemistry, Analytical Toxicology +13

Brain Temperature Alters Hydroxyl Radical Production during Cerebral Ischemia/Reperfusion in Rats

Ho Yeong Kil, Jing Zhang, Claude A. Piantadosi · Journal of Cerebral Blood Flow & Metabolism · 1996 · 292 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+

Chuang C. Chiueh, Gopal Krishna, Priya Tulsi et al. · Free Radical Biology and Medicine · 1992 · 235 citations

Life Sciences, Neurobiology, Neuroscience +15