Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS

Human Cells Lacking mtDNA: Repopulation with Exogenous Mitochondria by Complementation

Michael P. King, Giuseppe Attardi · Science · 1989 · 1.6K citations

De Novo Gene Disruptions in Children on the Autistic Spectrum

Ivan Iossifov, Michael Ronemus, Dan Levy et al. · Neuron · 2012 · 1.5K citations · Full text

Developmental Biology, Syndromic Autism, Genetic Disorder +8

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

Biosynthesis, Essential Role, Biochemistry +9

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

Sarah E. Calvo, Karl R. Clauser, Vamsi K. Mootha · Nucleic Acids Research · 2015 · 1.3K citations · Full text

Mitophagy, Genetics, Molecular Biology +21

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

Larry Reitzer, Burton M. Wice, David Kennell · Journal of Biological Chemistry · 1979 · 1.2K citations · Full text

Biosynthesis, Energy Metabolism, Biochemistry +11