Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis, +9

Nature

Molecular PhysiologyMitochondrial FunctionNatural SciencesGeneticsDna Replication +7

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

Yasemin Sancak, Andrew L. Markhard, Toshimori Kitami, +10

Science

Molecular BiologyMitochondrial UniporterMolecular GeneticsCytoskeletonCellular Physiology +18

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

Xiaoyan Bao, Shao‐En Ong, Olga Goldberger, +12

eLife

Reductive StressSystems BiologyMitochondrial FunctionBiochemistryHuman Cells +12

Hypoxia as a therapy for mitochondrial disease

Isha H. Jain, L. Zazzeron, Rahul Goli, +11

Science

Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns.

C.W. Kim, Olga Goldberger, Richard L. Gallo, +1

Molecular Biology of the Cell

Developmental BiologyHeparan Sulfate ProteoglycansMedicineCell InteractionGlycobiology +12

High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

Sarah E. Calvo, Elena J. Tucker, Alison G. Compton, +15

Nature Genetics

Identifies MutationsHuman ComplexSequencingNext-generation SequencingGenetics +9

Systematic identification of human mitochondrial disease genes through integrative genomics

Sarah E. Calvo, Mohit Jain, Xiaohui Xie, +7

Nature Genetics

Systematic IdentificationGenetic AnalysisFunctional GenomicsMitochondrial FunctionGenetics +7

Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse

Mary Ann Stepp, Heather E. Gibson, Purvi H. Gala, +9

Journal of Cell Science

DermatologyOcular Surface PhysiologyIntegrin Protein LevelsCellular PhysiologyMatrix Biology +14

Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3

Ofer Reizes, John Lincecum, Zihua Wang, +8

Cell

BiologyFeeding BehaviorSignal TransductionSynaptic TransmissionPhysiology +6

Hepatic NADH reductive stress underlies common variation in metabolic traits

Russell P. Goodman, Andrew L. Markhard, Hardik Shah, +14

Nature

Reductive StressMetabolic SyndromeMetabolic TraitsEnergy MetabolismHepatology +11