Nature Biotechnology · 2022 · 166 citations · 30 references
Life SciencesMolecular BiologyMolecular GeneticsRna ProcessingTranscriptionPolymerase Chain ReactionPrime EditingRna EngineeringRna Polymerase FunctionRna TranscriptionTranscription ElongationCircular Messenger RnaPrime Editing Computational DesignPrime Editing Reverse Transcriptase EngineeringPrimer Template Recognition
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Search-and-replace genome editing without double-strand breaks or donor DNA
Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis et al. · Nature · 2019 · 4.7K citations · Full text
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino et al. · Nature · 2014 · 2.9K citations
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue, Lars Zender, Cornelius Miething et al. · Nature · 2007 · 2.4K citations
Medicine, Cancer Biology, Oncology +16
A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
Marvin E. Tanenbaum, Luke A. Gilbert, Lei S. Qi et al. · Cell · 2014 · 1.6K citations · Full text
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
Hisaya Azuma, Nicole K. Paulk, Aarati R. Ranade et al. · Nature Biotechnology · 2007 · 824 citations · Full text