Zexiang Chen

A split prime editor with untethered reverse transcriptase and circular RNA template

Bin Liu, Xiaolong Dong, Haoyang Cheng et al. · Nature Biotechnology · 2022 · 156 citations

Bioinformatics, Engineering, Genetics +14

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo

Raed Ibraheim, Phillip W.L. Tai, Aamir Mir et al. · Nature Communications · 2021 · 109 citations · Full text

All-in-one Aav Vectors, Engineering, In Vivo Gene Therapy +19

5′-Modifications improve potency and efficacy of DNA donors for precision genome editing

Krishna S. Ghanta, Zexiang Chen, Aamir Mir et al. · eLife · 2021 · 71 citations · Full text

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

Shun‐Qing Liang, Pengpeng Liu, Karthikeyan Ponnienselvan et al. · Nature Methods · 2023 · 64 citations · Full text

Functional Genomics, Engineering, Medicine +11

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates

Bin Liu, Xiaolong Dong, Chunwei Zheng et al. · Nature Biotechnology · 2023 · 54 citations · Full text

Natural Sciences, Genetics, Genetic Engineering +9