Treadmill exercise improve recognition memory by TREM2 pathway to inhibit hippocampal microglial activation and neuroinflammation in Alzheimer's disease model

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell · 2017 · 5.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.9K citations · Full text

Life Sciences, Neurology, Neuroscience +14

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

Mychael V. Lourenco, Rudimar Luiz Frozza, Guilherme B. de Freitas et al. · Nature Medicine · 2018 · 931 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

Se Hoon Choi, Enjana Bylykbashi, Zena K. Chatila et al. · Science · 2018 · 820 citations · Full text

Medicine, Neurobiology, Neuroscience +17