Mychael V. Lourenco

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

Mychael V. Lourenco, Rudimar Luiz Frozza, Guilherme B. de Freitas et al. · Nature Medicine · 2018 · 882 citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Alzheimer's Disease +11

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

Mychael V. Lourenco, Julia R. Clarke, Rudimar Luiz Frozza et al. · Cell Metabolism · 2013 · 407 citations · Full text

Neurodegenerative Diseases, β-Amyloid Oligomers, Alzheimer's Disease +13

d-serine levels in Alzheimer’s disease: implications for novel biomarker development

Caroline Madeira, Mychael V. Lourenco, Charles Vargas-Lopes et al. · Translational Psychiatry · 2015 · 218 citations · Full text

Neurochemical Biomarkers, Social Sciences, D-serine Levels +16

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer’s disease

Maurício M. Oliveira, Mychael V. Lourenco, Francesco Longo et al. · Science Signaling · 2021 · 138 citations · Full text

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

Jordano Brito‐Moreira, Mychael V. Lourenco, Maurício M. Oliveira et al. · Journal of Biological Chemistry · 2017 · 85 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +8