Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, Kevin A. Guttenplan, Laura Clarke et al. · Nature · 2017 · 8K citations · Full text

Medicine, Neurobiology, Neuroscience +14

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell · 2017 · 5.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.6K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong, Victoria F. Beja-Glasser, Bianca M. Nfonoyim et al. · Science · 2016 · 3.4K citations · Full text

Life Sciences, Immunology, Neuroscience +17

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Susanne Krasemann, Charlotte Madore, Ron Cialic et al. · Immunity · 2017 · 3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16