Asparagine endopeptidase-targeted Ultrasound-responsive Nanobubbles Alleviate Tau Cleavage and Amyloid-β Deposition in an Alzheimer's Disease Model

Morris water maze: procedures for assessing spatial and related forms of learning and memory

Charles V. Vorhees, Michael T. Williams · Nature Protocols · 2006 · 4.6K citations · Full text

Social Sciences, Neuroscience, Psychology +14

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

Medicine, Cancer Biology, Oncology +16

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Paige E. Cramer, John R. Cirrito, Daniel W. Wesson et al. · Science · 2012 · 1K citations

Life Sciences, Neurobiology, Neuroscience +17

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease

Hyek Jin Kwon, Moon-Yong Cha, Dokyoon Kim et al. · ACS Nano · 2016 · 659 citations

Life Sciences, Neurobiology, Neuroscience +17

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

Zhentao Zhang, Mingke Song, Xia Liu et al. · Nature Medicine · 2014 · 487 citations · Full text

Life Sciences, Biochemistry, Neuroscience +13