The Journal of Organic Chemistry · 2021 · 50 citations · 77 references
Life SciencesBiochemistryPharmacologyNeurochemistryNeuropharmacologyRedox BiochemistryAntioxidant DefenseEnzyme InhibitionEnzyme KineticsOxidative Damage To BiomoleculesReactive Oxygen SpeciesAntioxidant PropertiesAntioxidantsCatecholamine BiochemistryDopamine OxidationElectron TransferElectron Transfer MechanismsPeroxidation ProcessesPh Dependence
. Our results from a homogeneous system and bilayers prove that catecholamines act as effective, radical trapping antioxidants with activity depending on the ionization status of the catechol moiety, as well as microenvironment: organization of the lipid system (emulsions vs bilayers) and interactions of catecholamines with the biomembrane.
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