A detrimental role of NLRP6 in host iron metabolism during Salmonella infection

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3K citations

Signal Transduction, Signaling Pathway, Cell Regulation +5

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, H. Kurokawa, Satoshi Waguri et al. · Nature Cell Biology · 2010 · 2.4K citations

Cell Autophagy, Mitophagy, Signal Transduction +10

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Edward A. Miao, Irina A. Leaf, Piper M. Treuting et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Inflammation, Virulence Factor, Apoptosis +13

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

Yoshinobu Ichimura, Satoshi Waguri, Yu‐shin Sou et al. · Molecular Cell · 2013 · 1.2K citations · Full text

Cell Autophagy, Mitophagy, Selective Autophagy +10

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhenyu Zhong, Atsushi Umemura, Elsa Sánchez‐López et al. · Cell · 2016 · 1.1K citations · Full text

Inflammation, Mitochondrial Function, Immunology +9