Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

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Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

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Medicine, Pharmacology, Pharmacotherapy +13

The Epidemiology of Sepsis in the United States from 1979 through 2000

Greg S. Martin, David M. Mannino, Stephanie Eaton et al. · New England Journal of Medicine · 2003 · 5.9K citations · Full text

Veterinary Medicine, Demography, Infectious Diseases +17

High-Dose Antithrombin III in Severe Sepsis

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Medicine, Pharmacology, Pharmacotherapy +17

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

F. J. Walker, Paul W. Sexton, Charles T. Esmon · Biochimica et Biophysica Acta (BBA) - Enzymology · 1979 · 480 citations

Medicine, Biochemistry, Hematology +14