Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis - Concepedia

Concepedia

Publication | Open Access

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

DOI Full Paper Access

6.1K

Citations

32

References

2001

Year

Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre, Steven P. LaRosa, Jean-François Dhainaut, Angel Lopez-Rodriguez, Jay S. Steingrub, Gary E. Garber, Jeffrey D. Helterbrand, E. Wesley Ely,

New England Journal of Medicine

Abstract

Treatment with drotrecogin alfa activated significantly reduces mortality in patients with severe sepsis and may be associated with an increased risk of bleeding.

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