Charles T. Esmon

Extracellular histones are major mediators of death in sepsis

Jun Xu, Xiaomei Zhang, Rosana Pelayo et al. · Nature Medicine · 2009 · 1.5K citations · Full text

Inflammation, Apoptosis, Immunology +6

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

Charles T. Esmon, Whyte G. Owen · Proceedings of the National Academy of Sciences · 1981 · 835 citations · Full text

Cardiac Muscle, Endothelial Cell Cofactor, Protein C Formation +23

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

Fabrizio Semeraro, Concetta T. Ammollo, James H. Morrissey et al. · Blood · 2011 · 820 citations · Full text

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

N L Esmon, Whyte G. Owen, Charles T. Esmon · Journal of Biological Chemistry · 1982 · 705 citations · Full text

Protein Chemistry, Proteinlipid Interaction, Protein Function +8

The Regulation of Natural Anticoagulant Pathways

Charles T. Esmon · Science · 1987 · 698 citations