Charles T. Esmon

Extracellular histones are major mediators of death in sepsis

Jun Xu, Xiaomei Zhang, Rosana Pelayo et al. · Nature Medicine · 2009 · 1.5K citations · Full text

Veterinary Medicine, Cell Biology, Molecular Biology +13

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

Fabrizio Semeraro, Concetta T. Ammollo, James H. Morrissey et al. · Blood · 2011 · 840 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

Charles T. Esmon, Whyte G. Owen · Proceedings of the National Academy of Sciences · 1981 · 838 citations · Full text

Medicine, Biochemistry, Molecular Biology +15

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

N L Esmon, Whyte G. Owen, Charles T. Esmon · Journal of Biological Chemistry · 1982 · 707 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

The Regulation of Natural Anticoagulant Pathways

Charles T. Esmon · Science · 1987 · 705 citations

Medicine, Hematology, Hemostasis +16