Concepedia

Extracellular histones are major mediators of death in sepsis

Jun Xu, Xiaomei Zhang, Rosana Pelayo, Marc Monestier, Concetta T. Ammollo, Fabrizio Semeraro, Fletcher B. Taylor, Naomi L. Esmon, Florea Lupu, Charles T. Esmon

Nature Medicine · 2009 · 1.5K citations · 17 references

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17

Neutrophil Extracellular Traps Kill Bacteria

Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al. · Science · 2004 · 10.1K citations

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Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre et al. · New England Journal of Medicine · 2001 · 6.1K citations · Full text

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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

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Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Stephen Clark, C. Adrienne, Samantha A. Tavener et al. · Nature Medicine · 2007 · 2.3K citations

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Immunodesign of experimental sepsis by cecal ligation and puncture

Daniel Rittirsch, Markus Huber‐Lang, Michael A. Flierl et al. · Nature Protocols · 2008 · 2.2K citations · Full text

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