Concepedia

Intestinal microbial communities and <i>Holdemanella</i> isolated from HIV+/− men who have sex with men increase frequencies of lamina propria CCR5 <sup>+</sup> CD4 <sup>+</sup> T cells

Eiko Yamada, Casey Martin, Nancy Moreno-Huizar, Jennifer Fouquier, C. Preston Neff, Sara L. Coleman, Jennifer M. Schneider, Jonathan Huber, Nichole Nusbacher, Martin D. McCarter,

Gut Microbes · 2021 · 28 citations · 60 references

DOIFull text

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Concepts

Abstract

isolates revealed unique cell wall and capsular components, which may be responsible for their differences in immunogenicity. These findings describe a novel mechanism potentially linking intestinal dysbiosis in MSM to HIV transmission and mucosal pathogenesis.

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