Design and Generation of a CRISPR Interference System for Genetic Repression and Essential Gene Analysis in the Fungal Pathogen Candida albicans

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Lei S. Qi, Matthew H. Larson, Luke A. Gilbert et al. · Cell · 2013 · 5.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria

Jason M. Peters, Alexandre Colavin, Handuo Shi et al. · Cell · 2016 · 786 citations · Full text

Life Sciences, Genetics, Microbiology +14

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Jeremy M. Rock, Forrest Hopkins, Alejandro Chavez et al. · Nature Microbiology · 2017 · 576 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Large‐scale essential gene identification in <i>Candida albicans</i> and applications to antifungal drug discovery

Terry Roemer, Bo Jiang, John Davison et al. · Molecular Microbiology · 2003 · 523 citations

Life Sciences, Molecular Biology, Molecular Genetics +17

The<i>Candida</i>Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data

Marek S. Skrzypek, Jonathan Binkley, Gail Binkley et al. · Nucleic Acids Research · 2016 · 479 citations · Full text

Life Sciences, Biology, Microbiology +17