Concepedia

Natural scaffolds-inspired synthesis of CF3-substituted macrolides enabled by Rh-catalyzed C–H alkylation macrocyclization

Tongyu Bi, Yi Xu, Xin Xu, Bixi Tang, Qing Yang, Yi Zang, Zhenyang Lin, Jia Li, Weibo Yang

Chinese Chemical Letters · 2021 · 14 citations · 36 references

DOI

Concepts

References

36

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

Joseph Heitman, N. Rao Movva, Michael N. Hall · Science · 1991 · 2K citations

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A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

Matthew W. Harding, David Uehling, Stuart L. Schreiber · Nature · 1989 · 1.4K citations

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A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

John J. Siekierka, Shirley H.Y. Hung, Martin Poe et al. · Nature · 1989 · 1K citations

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Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.

Suren N. Sehgal, Hinton J. Baker, Claude Vézina · The Journal of Antibiotics · 1975 · 958 citations · Full text

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