Theranostics · 2021 · 37 citations · 53 references
Life SciencesCell BiologyMolecular BiologyCancer GeneticsCellular MetabolismMolecular OncologyCancer Cell SignalingCancer MetabolismCancer TranscriptomicsMetabolic ReprogrammingMetabolic Reprogramming In CancerCancer Metabolic PhenotypingCell Cycle DynamicsCrispr-cas9 KnockoutDormant StagesMyc Proto-oncogeneOncogenic Myc SignalingQuiescenceQuiescence Maintenance
These results establish a rigorous experimental system for investigating cellular quiescence, uncover the high selectivity of c-Myc in activating OXPHOS genes in quiescent cells, and propose OXPHOS targeting as a potential therapeutic avenue to counter cancer cells in quiescence.
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Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
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