Concepedia

Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF

Rizwan Haq, Jonathan E. Shoag, Pedro Andreu-Pérez, Satoru Yokoyama, Hannah Edelman, Glenn C. Rowe, Dennie T. Frederick, Aeron D. Hurley, Abhinav Nellore, Andrew L. Kung,

Cancer Cell · 2013 · 815 citations · 64 references

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64

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.6K citations

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Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

Paul B. Chapman, Axel Hauschild, Caroline Robert et al. · New England Journal of Medicine · 2011 · 7.7K citations · Full text

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Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

Zhidan Wu, Pere Puigserver, Chen‐Yu Zhang et al. · Cell · 1999 · 4.1K citations · Full text

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