Concepedia

Development of a genetic algorithm and NONMEM workbench for automating and improving population pharmacokinetic/pharmacodynamic model selection

M. Ismail, Mark Sale, Yifan Yu, Nikhil Pillai, Sihang Liu, Beth R. Pflug, Robert R. Bies

Journal of Pharmacokinetics and Pharmacodynamics · 2021 · 27 citations · 7 references

DOI

Concepts

References

7

Genetic algorithms in search, optimization, and machine learning

Choice Reviews Online · 1989 · 49.3K citations

, , +14

Xpose—an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

E. Niclas Jonsson, Mats O. Karlsson · Computer Methods and Programs in Biomedicine · 1998 · 1K citations

, , +12

Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Lars Lindbom, Jakob Ribbing, E. Niclas Jonsson · Computer Methods and Programs in Biomedicine · 2004 · 730 citations

, , +1

Interaction between structural, statistical, and covariate models in population pharmacokinetic analysis

Janet R. Wade, Stuart L. Beal, Nancy C. Sambol · Journal of Pharmacokinetics and Biopharmaceutics · 1994 · 67 citations

, , +14

Nonlinearity detection: Advantages of nonlinear mixed-effects modeling

E. Niclas Jonsson, M. O. Karlsson, Janet R. Wade · AAPS PharmSci · 2000 · 50 citations

, , +17