Concepedia

Nonlinearity detection: Advantages of nonlinear mixed-effects modeling

E. Niclas Jonsson, M. O. Karlsson, Janet R. Wade

AAPS PharmSci · 2000 · 50 citations · 12 references

DOI

Concepts

References

12

Estimation of population characteristics of pharmacokinetic parameters from routine clinical data

Lewis B. Sheiner, Barr Rosenberg, Vinay V. Marathe · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 687 citations

, , +16

Evaluation of methods for estimating population pharmacokinetic parameters II. Biexponential model and experimental pharmacokinetic data

Lewis B. Sheiner, Stuart L. Beal · Journal of Pharmacokinetics and Biopharmaceutics · 1981 · 300 citations

, , +9

Estimating impossible curves using NONMEM

Rik C. Schoemaker, Adam F. Cohen · British Journal of Clinical Pharmacology · 1996 · 100 citations · Full text

, , +13

Is It Possible To Estimate the Parameters of the Sigmoid Emax Model with Truncated Data Typical of Clinical Studies?

Sandeep Dutta, Yoshiaki Matsumoto, William F. Ebling · Journal of Pharmaceutical Sciences · 1996 · 68 citations

, , +7

The deterministic identifiability of nonlinear pharmacokinetic models

K.R. Godfrey, William R. Fitch · Journal of Pharmacokinetics and Biopharmaceutics · 1984 · 38 citations

, , +11