Estimation of population characteristics of pharmacokinetic parameters from routine clinical data

Determination of Therapeutic and Toxic Serum Digoxin Concentrations by Radioimmunoassay

Thomas W. Smith, Vincent P. Butler, Edgar Haber · New England Journal of Medicine · 1969 · 589 citations

Heart Failure, Cardiovascular Toxicity, Tritium-labeled Digoxin +17

Modelling of individual pharmacokinetics for computer-aided drug dosage

Lewis B. Sheiner, Barr Rosenberg, Kenneth L. Melmon · Computers and Biomedical Research · 1972 · 372 citations

Medicine, Computer-aided Drug Dosage, Biostatistics +5

Fundamentals of Clinical Pharmacokinetics

Gerald E. Schumacher · American Journal of Health-System Pharmacy · 1976 · 367 citations

Systems Pharmacology, Molecular Pharmacology, Therapeutic Drug Monitoring +15

Digoxin Metabolism in the Elderly

Gordon A. Ewy, Geeta Kapadia, Linda L. Yao et al. · Circulation · 1969 · 261 citations

Heart Failure, Aging, Cardiovascular Pharmacology +20

A computer program for estimation of creatinine clearance from unstable serum creatinine levels, age, sex, and weight

Roger W. Jelliffe, Susan M. Jelliffe · Mathematical Biosciences · 1972 · 187 citations

Obesity, Metabolic Syndrome, Urology +11