Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

Hiroshi Watanabe, Yohei Miyamoto, Daisuke Honda et al. · Kidney International · 2013 · 356 citations

Urology, Renal Function, Biochemistry +12

Elevated Levels of the Reactive Metabolite Methylglyoxal Recapitulate Progression of Type 2 Diabetes

Alexandra Moraru, Janica L. Wiederstein, Daniel Pfaff et al. · Cell Metabolism · 2018 · 166 citations · Full text

Metabolic Syndrome, Elevated Levels, Metabolic Disorder +9

Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway

Fengtao Li, Yu Chen, Yongjun Li et al. · European Journal of Pharmacology · 2020 · 135 citations

Inflammation, Metabolic Syndrome, Ampk/sirt1/nf-κb Pathway +8

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways

Hailong Li, Zhongyuan Tang · Free Radical Biology and Medicine · 2018 · 134 citations

Reductive Stress, Biochemistry, Mitochondrial Function +10

Tangshen formula modulates gut Microbiota and reduces gut-derived toxins in diabetic nephropathy rats

Tingting Zhao, Haojun Zhang, Xingbin Yin et al. · Biomedicine & Pharmacotherapy · 2020 · 62 citations · Full text