Shumei Wang

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Chen Zhao, Katherine A. Cheng, Zandra E. Walton et al. · Nature · 2012 · 447 citations

Oncology, Oncogenic Agent, Medicine +9

GDC-0449—A potent inhibitor of the hedgehog pathway

Kirk Robarge, Shirley A. Brunton, Georgette M. Castanedo et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 385 citations · Full text

Molecular Pharmacology, Signaling Pathway, Molecular Pathway +6

RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles

Baoye He, Qiang Cai, Lulu Qiao et al. · Nature Plants · 2021 · 324 citations · Full text

Biology, Plant Molecular Biology, Engineering +12

Inactivation of Dnmt3b in Mouse Embryonic Fibroblasts Results in DNA Hypomethylation, Chromosomal Instability, and Spontaneous Immortalization

Jonathan Dodge, Masaki Okano, Naomi Tsujimoto et al. · Journal of Biological Chemistry · 2005 · 274 citations · Full text

Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

Daniel P. Sutherlin, Linda Bao, Megan Berry et al. · Journal of Medicinal Chemistry · 2011 · 212 citations · Full text

Translational Pharmacology, Pre-clinical Pharmacology, Molecular Pharmacology +20