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Evaluating Stability and Activity of SARS-CoV-2 PLpro for High-throughput Screening of Inhibitors

Rimanshee Arya, Vishal Prashar, Mukesh Kumar

Molecular Biotechnology · 2021 · 20 citations · 13 references

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References

13

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Dong Hyuk Shin, Rukmini Mukherjee, Diana Grewe et al. · Nature · 2020 · 1.2K citations · Full text

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The Papain-Like Protease of Severe Acute Respiratory Syndrome Coronavirus Has Deubiquitinating Activity

Naina Barretto, Dalia Jukneliene, Kiira Ratia et al. · Journal of Virology · 2005 · 612 citations · Full text

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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

Kiira Ratia, Scott D. Pegan, Jun Takayama et al. · Proceedings of the National Academy of Sciences · 2008 · 533 citations · Full text

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Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

Theresa Klemm, Gregor Ebert, Dale J. Calleja et al. · The EMBO Journal · 2020 · 494 citations · Full text

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Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design

Wioletta Rut, Zongyang Lv, Mikołaj Żmudziński et al. · Science Advances · 2020 · 483 citations · Full text

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