A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

Kiira Ratia, Scott D. Pegan, Jun Takayama, +10

Proceedings of the National Academy of Sciences

Viral ReplicationMolecular BiologyAntiviral DrugViral Structural ProteinChemical Biology +15

Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease

Brendan T. Freitas, Ian A. Durie, Jackelyn Murray, +6

ACS Infectious Diseases

Viral PathogenesisImmunologyMolecular BiologyInnate ImmunityViral Structural Protein +19

Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species

Courtney M. Daczkowski, John V. Dzimianski, Jozlyn R. Clasman, +3

Journal of Molecular Biology

Virus StructureMolecular VirologyNatural SciencesMedicinePathogenesis +8

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

Florine E. M. Scholte, Marko Zivcec, John V. Dzimianski, +7

Cell Reports

Isg15 Specific ProteaseMolecular VirologyPathogenesisImmunologyViral Pathogenesis +7

Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression

Sung‐Jin Kim, Omar Awad Alsaidan, Octavia Goodwin, +13

Cancer Research

Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory Activities

Arup Maiti, P. Venkat Reddy, Megan Sturdy, +5

Journal of Medicinal Chemistry

Combinatorial ChemistryBioorganic ChemistryAldo-keto ReductaseChemical BiologyMedicinal Chemistry +15

Structural Analysis of a Viral Ovarian Tumor Domain Protease from the Crimean-Congo Hemorrhagic Fever Virus in Complex with Covalently Bonded Ubiquitin

Glenn C. Capodagli, Marissa A. McKercher, Erica A. Baker, +3

Journal of Virology

EngineeringImmunologyViral PathogenesisMolecular BiologyPathology +16

An Antimicrobial Guanidine-Bearing Sesterterpene from the Cultured Cyanobacterium <i>Scytonema</i> sp.

Shunyan Mo, Aleksej Krunić, Scott D. Pegan, +2

Journal of Natural Products

Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles

Marko Zivcec, Maureen G. Metcalfe, César G. Albariño, +4

PLoS neglected tropical diseases

Viral DiagnosticsViral PathogenesisImmunologyViral Structural ProteinImmune System +16

A Noncompetitive Inhibitor for<i>Mycobacterium tuberculosis</i>’s Class IIa Fructose 1,6-Bisphosphate Aldolase

Glenn C. Capodagli, Wafik G. Sedhom, Mary Jackson, +2

Biochemistry

Class IiBiosynthesisAntimicrobial Drug DiscoveryAldo-keto ReductaseBiochemistry +11