Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes

Cellpose: a generalist algorithm for cellular segmentation

Carsen Stringer, Michalis Michaelos, Marius Pachitariu · Nature Methods · 2020 · 4.4K citations

Computing, Biology, Cell Biology +12

A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

Jens C. Brüning, M.Dodson Michael, Jonathon N. Winnay et al. · Molecular Cell · 1998 · 1.2K citations · Full text

Medicine, Endocrinology, Molecular Genetics +14

Amphiphysin 2 (Bin1) and T-Tubule Biogenesis in Muscle

Eunkyung Lee, Melissa Marcucci, Laurie Daniell et al. · Science · 2002 · 466 citations

Life Sciences, Cell Biology, Physiology +17

Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy

Anne-Sophie Nicot, Anne Toussaint, Valérie Tosch et al. · Nature Genetics · 2007 · 433 citations

Life Sciences, Genetics, Molecular Genetics +12

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

Charlotte Fugier, Arnaud F. Klein, Caroline Hammer et al. · Nature Medicine · 2011 · 330 citations

Medicine, Genetics, Molecular Biology +11