Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS

Identification of multiple sources of charge heterogeneity in a recombinant antibody

Reed J. Harris, Bruce Kabakoff, Frank Macchi et al. · Journal of Chromatography B Biomedical Sciences and Applications · 2001 · 503 citations

Pharmacy, Biochemistry, Molecular Biology +16

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

Damian J. Houde, Yucai Peng, Steven A. Berkowitz et al. · Molecular & Cellular Proteomics · 2010 · 393 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

In Vivo Deamidation Characterization of Monoclonal Antibody by LC/MS/MS

Lihua Huang, Jirong Lu, Victor J. Wroblewski et al. · Analytical Chemistry · 2005 · 265 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

Josef Vlasak, Marie Claire Bussat, Shi‐Yi Wang et al. · Analytical Biochemistry · 2009 · 246 citations

Pharmacy, Chemical Biology, Molecular Biology +13

Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors

Andrea Bertolotti‐Ciarlet, Weirong Wang, Rebecca Lownes et al. · Molecular Immunology · 2009 · 231 citations

Life Sciences, Biochemistry, Immunology +8