Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection

Timothy W. Baba, Vladimír Liška, Regina Hofmann‐Lehmann, +16

Nature Medicine

Human RetrovirusImmunodeficienciesImmunologyAntiviral ResponseIgg1 Subtype Protect +6

Contribution of Variable Domains to the Stability of Humanized IgG1 Monoclonal Antibodies

Roxana Ionescu, Josef Vlasak, Colleen Price, +1

Journal of Pharmaceutical Sciences

Autoimmune DiseaseImmunologyImmunodominanceAntibody ScreeningAntigen Processing +11

Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies

Weirong Wang, Josef Vlasak, Yunsong Li, +7

Molecular Immunology

InflammationAllergyAutoimmune DiseaseSerum Half-lifeBioanalysis +10

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

Josef Vlasak, Marie Claire Bussat, Shi‐Yi Wang, +7

Analytical Biochemistry

Immunocytochemical TechniqueAllergyAutoimmune DiseaseAsparagine DeamidationPathogenesis +10

Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors

Andrea Bertolotti‐Ciarlet, Weirong Wang, Rebecca Lownes, +8

Molecular Immunology

InflammationSignal TransductionSignaling PathwayCell SignalingMedicine +8

The Farmland Rental Paradox: Extreme land ownership fragmentation as a new form of land degradation

Petr Sklenička, Vratislava Janovska, Miroslav Šálek, +1

Land Use Policy

HousingEconomicsNew FormLand DevelopmentLand Use +11

Postnatal Passive Immunization of Neonatal Macaques with a Triple Combination of Human Monoclonal Antibodies against Oral Simian-Human Immunodeficiency Virus Challenge

Regina Hofmann‐Lehmann, Josef Vlasak, Robert A. Rasmussen, +19

Journal of Virology

β-Elimination and Peptide Bond Hydrolysis:  Two Distinct Mechanisms of Human IgG1 Hinge Fragmentation upon Storage

Steven L. Cohen, Colleen Price, Josef Vlasak

Journal of the American Chemical Society

Protein ChemistryDistinct MechanismsIgg1 Degradation ProductPeptide Bond HydrolysisProtein Function +12

Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation.

Regina Hofmann‐Lehmann, Josef Vlasak, Alison L Williams, +5

PubMed

Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

Regina Hofmann‐Lehmann, Josef Vlasak, Alison L Williams, +5

AIDS

ImmunodeficienciesViral PathogenesisImmunologyPathologyImmunodominance +21