Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S.P. Rao, Miriam Huntley, Neva C. Durand et al. · Cell · 2014 · 9.9K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

The Astropy Project: Building an Open-science Project and Status of the v2.0 Core Package^*

Adrian M. Price-Whelan, Brigitta Sipőcz, Hans Moritz Günther et al. · The Astronomical Journal · 2018 · 7.4K citations · Full text

Natural Sciences, Astronomy, Astrophysics +5

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija et al. · Science · 2018 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +17

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Darío G. Lupiáñez, Katerina Kraft, Verena Heinrich et al. · Cell · 2015 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome

Tom Sexton, Eitan Yaffe, Ephraim Kenigsberg et al. · Cell · 2012 · 2.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16