Darío G. Lupiáñez

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Darío G. Lupiáñez, Katerina Kraft, Verena Heinrich et al. · Cell · 2015 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Polymer physics predicts the effects of structural variants on chromatin architecture

Simona Bianco, Darío G. Lupiáñez, Andrea M. Chiariello et al. · Nature Genetics · 2018 · 258 citations · Full text

Life Sciences, Biophysics, Molecular Biology +16

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice

Katerina Kraft, Sinje Geuer, Anja J. Will et al. · Cell Reports · 2015 · 237 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

Bjørt K. Kragesteen, Malte Spielmann, Christina Paliou et al. · Nature Genetics · 2018 · 213 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +16

Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)

Anja J. Will, Giulia Cova, Marco Osterwalder et al. · Nature Genetics · 2017 · 137 citations · Full text

Medicine, Genetics, Molecular Genetics +8