Novel 4,5-dihydrospiro[benzo[c]azepine-1,1′-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

Junko Murai, Shar-yin N. Huang, Benu Brata Das et al. · Cancer Research · 2012 · 2.1K citations · Full text

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

Bryan A. Gibson, Yajie Zhang, Hong Jiang et al. · Science · 2016 · 371 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +20

Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines.

Carol A. Delaney, L Z Wang, Suzanne Kyle et al. · PubMed · 2000 · 206 citations

Novel Parp Inhibitors, Pharmacotherapy, Tumor Biology +17

The Suzuki–Miyaura Coupling of Nitroarenes

M. Ramu Yadav, Masahiro Nagaoka, Myuto Kashihara et al. · Journal of the American Chemical Society · 2017 · 196 citations

PARP1 Inhibitors: Antitumor Drug Design

N. V. Malyuchenko, E. Yu. Kotova, Olga I. Kulaeva et al. · Acta Naturae · 2015 · 103 citations · Full text