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Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

Prenitha Mercy Ignatius Arokia Doss, Muhammad Umair, Joanie Baillargeon, Mohamed Reda Fazazi, Neva J. Fudge, Irshad Akbar, Asmita Pradeep Yeola, John B. Williams, Mickaël Leclercq, Charles Joly-Beauparlant,

Cell Reports · 2021 · 42 citations · 79 references

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Abstract

T cells from MS-affected individuals. Our data indicate that male sex chromosomal complement critically regulates Th17 cell pathogenicity.

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