Concepedia

Th17 Cell Pathogenicity

Th17 Cell Pathogenicity is a pathogenic immune mechanism characterized by the aberrant activation and effector function of T helper 17 cells, distinguished from other T-cell-mediated pathologies by their specific production of pro-inflammatory cytokines, particularly IL-17, that drive tissue inflammation and autoimmunity.

320

Publications

37.6K

Citations

2.4K

Authors

692

Institutions

Publications per year

2017–2026

182

Parents

Publications

320

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

, , +16

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

Markus Kleinewietfeld, Arndt Manzel, Jens Titze et al. · Nature · 2013 · 1.4K citations · Full text

, , +16

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Kamran Ghoreschi, Arian Laurence, Xiang‐Ping Yang et al. · Nature · 2010 · 1.4K citations

, , +14

Induction and molecular signature of pathogenic TH17 cells

Youjin Lee, Amit Awasthi, Nir Yosef et al. · Nature Immunology · 2012 · 1.2K citations · Full text

, , +14

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa et al. · Nature Medicine · 2013 · 1.1K citations

, , +17

1–5 of 320

Authors

2.4K

  1. VK
    Vijay K. Kuchroo

    Brigham and Women's Hospital, United States

    14 publications · 10.8K citations

    13

    h-index

  2. AR
    Aviv Regev

    Broad Institute, United States

    8 publications · 3.6K citations

    8

    h-index

  3. XL
    Xiuxing Liu

    Sun Yat-sen University, China

    5 publications · 189 citations

    7

    h-index

  4. WS
    Wenru Su

    Sun Yat-sen University, China

    5 publications · 189 citations

    7

    h-index

  5. RA
    Richard A. Flavell

    Yale University, United States

    7 publications · 483 citations

    7

    h-index

1–5 of 2.4K

Institutions

692

  1. Harvard University

    Cambridge, United States

    24 h-index

    154 publications

    59.3K citations

  2. Brigham and Women's Hospital

    Boston, United States

    19 h-index

    113 publications

    72.5K citations

  3. Broad Institute

    Cambridge, United States

    14 h-index

    62 publications

    19.7K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    18 publications

    4.6K citations

  5. National Institutes of Health

    Bethesda, United States

    14 h-index

    80 publications

    28.8K citations

  6. Yale University

    New Haven, United States

    12 h-index

    23 publications

    6.4K citations

  7. Sun Yat-sen University

    Guangzhou, China

    11 h-index

    63 publications

    3.2K citations

  8. University of Michigan

    Ann Arbor, United States

    10 h-index

    27 publications

    1.7K citations

1–8 of 692

Venues

  1. The Journal of Immunology

    JI · 35 publications · 4K citations

    29

    h-index

  2. Nature Communications

    16 publications · 1.6K citations

    16

    h-index

  3. Frontiers in Immunology

    12 publications · 520 citations

    13

    h-index

  4. PLoS ONE

    9 publications · 706 citations

    9

    h-index

  5. Immunity

    9 publications · 1.3K citations

    9

    h-index

1–5