Concepedia

The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs

Hugo Rolando Vaca, Ana M. Celentano, María A. Toscanini, Tino Heimburg, Ehab Ghazy, Patrik Zeyen, Alexander‐Thomas Hauser, Guilherme Oliveira, Marı́a Celina Elissondo, Manfred Jung,

PLoS neglected tropical diseases · 2021 · 20 citations · 46 references

DOIFull text

Open access

Abstract

The results presented here suggest that HDAC inhibitors represent novel and potent drug candidates against cestodes and pave the way to understanding the roles of HDACs in these parasites.

References

46

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Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

Martin Marek, Srinivasaraghavan Kannan, Alexander‐Thomas Hauser et al. · PLoS Pathogens · 2013 · 170 citations · Full text

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