Srinivasaraghavan Kannan

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

Pau Castel, Haley Ellis, Ružica Bago et al. · Cancer Cell · 2016 · 222 citations · Full text

Molecular Physiology, Signal Transduction, Pi3kα Inhibition +9

Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins

Luigi Petrone, Akshita Kumar, Clarinda Nataria Sutanto et al. · Nature Communications · 2015 · 186 citations · Full text

Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

Martin Marek, Srinivasaraghavan Kannan, Alexander‐Thomas Hauser et al. · PLoS Pathogens · 2013 · 170 citations · Full text

Histone Modifications, Generic Hdac Inhibitors, Antiparasitic Agent +28

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer

Marta Palafox, Laia Monserrat, Meritxell Bellet et al. · Nature Communications · 2022 · 113 citations · Full text

Enhanced sampling of peptide and protein conformations using replica exchange simulations with a peptide backbone biasing‐potential

Srinivasaraghavan Kannan, Martin Zacharias · Proteins Structure Function and Bioinformatics · 2006 · 110 citations