Haley Ellis

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

Dejan Juric, Pau Castel, Malachi Griffith et al. · Nature · 2014 · 561 citations · Full text

Signal Transduction, Clinical Resistance, Signaling Pathway +8

Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells

David T. Ting, Ben S. Wittner, Matteo Ligorio et al. · Cell Reports · 2014 · 527 citations · Full text

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer

Ana Bosch, Zhiqiang Li, Anna Bergamaschi et al. · Science Translational Medicine · 2015 · 418 citations · Full text

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

Pau Castel, Haley Ellis, Ružica Bago et al. · Cancer Cell · 2016 · 222 citations · Full text

Molecular Physiology, Signal Transduction, Pi3kα Inhibition +9

Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer

Jessica J. Tao, Pau Castel, Nina Radosevic‐Robin et al. · Science Signaling · 2014 · 164 citations · Full text

Breast Oncology, Oncology, Signaling Pathway +15