Jane B. Trepel

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Jennifer S. Isaacs, Yun Jin Jung, David R. Mole et al. · Cancer Cell · 2005 · 935 citations · Full text

Urology, Renal Function, Fumarate Hydratase +6

IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis

Yunjin Jung, Jennifer S. Isaacs, Sunmin Lee et al. · The FASEB Journal · 2003 · 664 citations

Hif-1alpha Protein, Immunology, Immune Regulation +16

Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor

Denise A. Yardley, Roohi Ismail‐Khan, Bohuslav Melichar et al. · Journal of Clinical Oncology · 2013 · 410 citations · Full text

Phase I and Pharmacokinetic Study of MS-275, a Histone Deacetylase Inhibitor, in Patients With Advanced and Refractory Solid Tumors or Lymphoma

Qin Ryan, Donna Headlee, Milin Acharya et al. · Journal of Clinical Oncology · 2005 · 406 citations · Full text

The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties

Sara J. Felts, Barbara Owen, Phuongmai Nguyen et al. · Journal of Biological Chemistry · 2000 · 367 citations · Full text