Concepedia

Author

Patrik Zeyen

Martin Luther University Halle-Wittenberg

Also Known As

Patrik Zeyen

12

Publications

311

Citations

8

H-Index

26

Concepts

All Affiliations

Martin Luther University Halle-WittenbergInsermUniversité de StrasbourgInstitut de génétique et de biologie moléculaire et cellulaireUniversity of Freiburg
PZ

About

Patrik Zeyen is an author at Martin Luther University Halle-Wittenberg specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

173

2

Natural Sciences

3

3

121

3

Biochemistry

3

3

102

4

Chemical Biology

3

3

121

5

Cell Biology

2

2

72

Patrik Zeyen

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8

Publications

305

Citations

8

H-Index

YearCitations

Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity

Tino Heimburg, Fiona R. Kolbinger, Patrik Zeyen,

Journal of Medicinal Chemistry

2017

91

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

Hany S. Ibrahim, Mohamed Abdelsalam, Yanira Zeyn,

International Journal of Molecular Sciences

2021

50

Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells

Patrik Zeyen, Yanira Zeyn, Daniel Herp,

European Journal of Medicinal Chemistry

2022

36

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

Salma Darwish, Ehab Ghazy, Tino Heimburg,

International Journal of Molecular Sciences

2022

36

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1

Ehab Ghazy, Patrik Zeyen, Daniel Herp,

European Journal of Medicinal Chemistry

2020

35

Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (smHDAC8) Inhibitors

Conrad V. Simoben, Ehab Ghazy, Patrik Zeyen,

Molecules

2021

21

The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs

Hugo Rolando Vaca, Ana M. Celentano, María A. Toscanini,

PLoS neglected tropical diseases

2021

20

Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis

Ehab Ghazy, Tino Heimburg, Julien Lancelot,

European Journal of Medicinal Chemistry

2021

16

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