Yanira Zeyn

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

Hany S. Ibrahim, Mohamed Abdelsalam, Yanira Zeyn et al. · International Journal of Molecular Sciences · 2021 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells

Patrik Zeyen, Yanira Zeyn, Daniel Herp et al. · European Journal of Medicinal Chemistry · 2022 · 36 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3

Vanessa Wachholz, Al‐Hassan M. Mustafa, Yanira Zeyn et al. · Archives of Toxicology · 2021 · 27 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

Melisa Halilovic, Mohamed Abdelsalam, Joanna Zabkiewicz et al. · Leukemia · 2024 · 23 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity

Franziska Haase, Jana Pöhmerer, Mina Yazdi et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2023 · 19 citations

Life Sciences, Immunology, Molecular Biology +16