<scp>CircRNA circ‐IQGAP1</scp> Knockdown Alleviates Interleukin‐1β‐Induced Osteoarthritis Progression <scp><i>via</i></scp> Targeting <scp>miR‐671‐5p/TCF4</scp>

Abstract

Circ-IQGAP1 knockdown attenuated IL-1β-caused chondrocyte apoptosis, inflammatory injury, and extracellular matrix degradation. Circ-IQGAP1 could regulate miR-671-5p/TCF4 axis to modulate IL-1β-caused chondrocyte damage. Circ-IQGAP1 might act as a new target for the treatment of OA.