Concepedia

Publication | Open Access

CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene

DOIFull Paper Access

298

Citations

25

References

2019

Year

Shuying Shen, Yizheng Wu, Junxin Chen, Ziang Xie, Kangmao Huang, Gangliang Wang, Yute Yang, Weiyu Ni, Zhijun Chen, Peihua Shi,
Annals of the Rheumatic Diseases

Abstract

Our results reveal an important role for a novel circRNA-CircSERPINE2 in OA progression. CircSERPINE2 overexpression could alleviate HCs apoptosis and promote anabolism of ECM through miR-1271-ERG pathway. It provides a potentially effective therapeutic strategy for OA progression.

References

YearCitations

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