Design and synthesis of novel glycyrrhetin ureas as anti-inflammatory agents for the treatment of acute kidney injury

Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospitalized Patients

Glenn M. Chertow, Elisabeth Burdick, Melissa Honour et al. · Journal of the American Society of Nephrology · 2005 · 3.4K citations

Critical Care Management, Serum Creatinine, Hemodialysis +13

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

Diego Martín‐Sánchez, Olga Ruiz‐Andrés, Jonay Poveda et al. · Journal of the American Society of Nephrology · 2016 · 544 citations · Full text

Iron Metabolism, Lipid Peroxidation, Renal Pathology +19

Pyrazole Urea-Based Inhibitors of p38 MAP Kinase:  From Lead Compound to Clinical Candidate

John R. Regan, Steffen Breitfelder, Pier F. Cirillo et al. · Journal of Medicinal Chemistry · 2002 · 349 citations · Full text

Drug Target, P38 Map Kinase, Atp Binding Site +20

Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization

Kiyoshi Okamoto, Megumi Ikemori‐Kawada, A. Jestel et al. · ACS Medicinal Chemistry Letters · 2014 · 263 citations · Full text

Inflammatory cytokines in acute renal failure

Ganesan Ramesh, William Reeves · Kidney International · 2004 · 204 citations · Full text

Glomerular Disease, Inflammation, Inflammatory Cytokines +8