Concepedia

Carnitine transporter CT2 (SLC22A16) is over-expressed in acute myeloid leukemia (AML) and target knockdown reduces growth and viability of AML cells

Yan Wu, Rose Hurren, Neil MacLean, Marcela Gronda, Yulia Jitkova, Mahadeo A. Sukhai, Mark D. Minden, Aaron D. Schimmer

APOPTOSIS · 2015 · 53 citations · 17 references

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17

A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

Jason Moffat, Dorre A. Grueneberg, Xiaoping Yang et al. · Cell · 2006 · 1.9K citations · Full text

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BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Eleni D. Lagadinou, Alexander Sach, Kevin P. Callahan et al. · Cell stem cell · 2013 · 1.4K citations · Full text

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Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Ismael Samudio, Romain Harmancey, Michael Fiegl et al. · Journal of Clinical Investigation · 2009 · 699 citations · Full text

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Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Marko Škrtić, Shrivani Sriskanthadevan, Bozhena Jhas et al. · Cancer Cell · 2011 · 694 citations

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Role of carnitine in disease

Judith Flanagan, Peter A. Simmons, Joseph Vehige et al. · Nutrition & Metabolism · 2010 · 615 citations · Full text

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